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  2. Sodium–potassium pump - Wikipedia

    en.wikipedia.org/wiki/Sodiumpotassium_pump

    The sodium–potassium pump was discovered in 1957 by the Danish scientist Jens Christian Skou, who was awarded a Nobel Prize for his work in 1997. Its discovery marked an important step forward in the understanding of how ions get into and out of cells, and it has particular significance for excitable cells such as nerve cells , which depend ...

  3. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    Potassium ions (K +) begin to move down the electrochemical gradient (in favor of the concentration gradient and the newly established electrical gradient). As potassium moves out of the cell the potential within the cell decreases and approaches its resting potential once more. The sodium potassium pump works continuously throughout this ...

  4. Transport protein - Wikipedia

    en.wikipedia.org/wiki/Transport_protein

    Schematic description of the mechanism of the sodium-potassium pump. Four consecutive steps are shown, from left to right. (1) Three sodium ions enter the transporter on the cell internal side. (2) A phosphorylated group is added to the transporter from ATP. This causes the transporter to close on the inside and open on the outside. The sodium ...

  5. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    e) Sodium-potassium pump. In the stages of an action potential, the permeability of the membrane of the neuron changes. At the resting state (1), sodium and potassium ions have limited ability to pass through the membrane, and the neuron has a net negative charge inside.

  6. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    For example, the sodium (Na +) and potassium (K +) ions are maintained by the sodium-potassium pump which uses energy (in the form of adenosine triphosphate (ATP)) to move three Na + out of the cell and two K + into the cell. Another example is the sodium-calcium exchanger which removes one Ca 2+ from the cell for three Na + into the cell. [12]

  7. Active transport - Wikipedia

    en.wikipedia.org/wiki/Active_transport

    Active transport is essential for various physiological processes, such as nutrient uptake, hormone secretion, and nig impulse transmission. For example, the sodium-potassium pump uses ATP to pump sodium ions out of the cell and potassium ions into the cell, maintaining a concentration gradient essential for cellular function. Active transport ...

  8. Membrane transport protein - Wikipedia

    en.wikipedia.org/wiki/Membrane_transport_protein

    Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, three sodium ions are extruded from and two potassium ions are imported into the cell. Active transport is the movement of a substance across a membrane against its concentration gradient. This ...

  9. Sodium in biology - Wikipedia

    en.wikipedia.org/wiki/Sodium_in_biology

    The sodium–potassium pump, a critical enzyme for regulating sodium and potassium levels in cells. Sodium ions (Na +) are necessary in small amounts for some types of plants, [1] but sodium as a nutrient is more generally needed in larger amounts [1] by animals, due to their use of it for generation of nerve impulses and for maintenance of electrolyte balance and fluid balance.