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The tubular heart or primitive heart tube is the earliest stage of heart development. [1] The heart is the first organ to develop during human embryonic development. [2]From the inflow to the outflow, the tubular heart consists of sinus venosus, primitive atrium, the primitive ventricle, the bulbus cordis, and truncus arteriosus. [3]
Heart development, also known as cardiogenesis, refers to the prenatal development of the heart. This begins with the formation of two endocardial tubes which merge to form the tubular heart, also called the primitive heart tube. The heart is the first functional organ in vertebrate embryos.
The endocardial tubes have an intimate proximity to the foregut or pharyngeal endoderm. [1] As folding of the embryo in the horizontal plane initiates in the 4th week of gestation, the endocardial tubes meet in the midline to form the primitive heart tube, which will eventually develop into the histologically definitive endocardium.
The flap of cartilage called the epiglottis stops food from entering the larynx. In humans, the pharynx is part of the digestive system and the conducting zone of the respiratory system . (The conducting zone—which also includes the nostrils of the nose , the larynx , trachea , bronchi , and bronchioles —filters, warms and moistens air and ...
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
During fusion, the heart tube is patterned along the anterior/posterior axis for the various regions and chambers of the heart. The surrounding mesocardium degenerates to leave the primitive heart attached only by its arterial and venous ends, which are anatomically fixed to the pharyngeal arches and the septum transversum, respectively.
Pattern of the pharyngeal arches. I-IV pharyngeal arches, 1–4 pharyngeal pouches (inside) and/or pharyngeal grooves (outside) a Tuberculum laterale b Tuberculum impar c Foramen cecum d Ductus thyreoglossus e Sinus cervicalis. The pharyngeal apparatus is an embryological structure. [1] [2] It consists of: pharyngeal grooves (from ectoderm)
The region where the crescentic masses of the ectoderm and endoderm come into direct contact with each other constitutes a thin membrane, the buccopharyngeal membrane (or oropharyngeal membrane), which forms a septum between the primitive mouth and pharynx.