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  2. Early-onset Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Early-onset_Alzheimer's...

    Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia; it usually occurs in old age. Familial Alzheimer's disease (FAD or EOFAD for early onset) is an inherited and uncommon form of AD. Familial AD usually strikes earlier in life, defined as before the age of 65.

  3. Familial Alzheimer-like prion disease - Wikipedia

    en.wikipedia.org/wiki/Familial_Alzheimer-like...

    Familial Alzheimer-like prion disease is an exceptionally rare inherited prion disease. Its name comes from its presentation, which is similar to Alzheimer's disease.

  4. Swedish mutation - Wikipedia

    en.wikipedia.org/wiki/Swedish_mutation

    The Swedish mutation, or familial Alzheimer's disease genetic mutation, is one of the most well known genetic variations that causes early-onset familial Alzheimer's disease. [ 1 ] History

  5. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    A Japanese pedigree of familial Alzheimer's disease was found to be associated with a deletion mutation of codon 693 of APP. [74] This mutation and its association with Alzheimer's disease was first reported in 2008, [75] and is known as the Osaka mutation. Only homozygotes with this mutation have an increased risk of developing Alzheimer's ...

  6. Presenilin - Wikipedia

    en.wikipedia.org/wiki/Presenilin

    In patients with Alzheimer's disease (autosomal dominant hereditary), mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP) can be found. The majority of these cases carry mutant presenilin genes. An important part of the disease process in Alzheimer's disease is the accumulation of Amyloid beta (Aβ

  7. The most promising breakthrough in Alzheimer’s treatment is ...

    www.aol.com/news/most-promising-breakthrough...

    The devastation of failed Alzheimer's drug trials is requiring people to open their minds to new approaches, methods, and disciplines. The most promising breakthrough in Alzheimer’s treatment is ...

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