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Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [ 1 ]
While many of the current H5N1 strains circulating in birds can generate a dangerous cytokine storm in healthy adult humans, the ultimate pandemic strain might arise from a less-lethal strain, or its current level of lethality might be lost in the adaptation to a human host.
Highly pathogenic H5N1 avian influenza in a human appears to be far worse, killing over 50% of humans reported infected with the virus, although it is unknown how many cases (with milder symptoms) go unreported. In one case, a boy with H5N1 experienced diarrhea followed rapidly by a coma without developing respiratory or flu-like symptoms. [41]
Any time a person catches H5N1, or bird flu, their infection is a chance for the virus to mutate in the wrong direction. When someone dies from the bird flu—as an elderly Louisiana man did on ...
Among them are recent detections of the virus in wastewater and signs of dangerous mutations. ... For one, the bird flu virus — known as H5N1 — has spread uncontrolled in animals, including ...
The CDC said that a sporadic case of severe H5N1 bird flu illness in a person is not unexpected as has previously been experienced in other countries during 2024 and prior years, including in ...
In October 2004 researchers discovered H5N1 is far more dangerous than previously believed because waterfowl, especially ducks, were directly spreading the highly pathogenic strain of H5N1 to chickens, crows, pigeons, and other birds and that it was increasing its
In contrast, H5N1 often kills birds that catch it, so it is classified as a highly pathogenic avian influenza. To complicate matters, although bird flu viruses primarily prey on birds, they can ...