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In null-hypothesis significance testing, the p-value [note 1] is the probability of obtaining test results at least as extreme as the result actually observed, under the assumption that the null hypothesis is correct. [2] [3] A very small p-value means that such an extreme observed outcome would be very unlikely under the null hypothesis.
A volcano plot is constructed by plotting the negative logarithm of the p value on the y axis (usually base 10). This results in data points with low p values (highly significant) appearing toward the top of the plot. The x axis is the logarithm of the fold change between the two conditions. The logarithm of the fold change is used so that ...
The p-value for the permutation test is the proportion of the r values generated in step (2) that are larger than the Pearson correlation coefficient that was calculated from the original data. Here "larger" can mean either that the value is larger in magnitude, or larger in signed value, depending on whether a two-sided or one-sided test is ...
As an example, if the two distributions do not overlap, say F is below G, then the P–P plot will move from left to right along the bottom of the square – as z moves through the support of F, the cdf of F goes from 0 to 1, while the cdf of G stays at 0 – and then moves up the right side of the square – the cdf of F is now 1, as all points of F lie below all points of G, and now the cdf ...
Successive parabolic interpolation is a technique for finding the extremum (minimum or maximum) of a continuous unimodal function by successively fitting parabolas (polynomials of degree two) to a function of one variable at three unique points or, in general, a function of n variables at 1+n(n+3)/2 points, and at each iteration replacing the "oldest" point with the extremum of the fitted ...
In statistical hypothesis testing, p-rep or p rep has been proposed as a statistical alternative to the classic p-value. [1] Whereas a p-value is the probability of obtaining a result under the null hypothesis, p-rep purports to compute the probability of replicating an effect. The derivation of p-rep contained significant mathematical errors.
The Šidák correction is derived by assuming that the individual tests are independent.Let the significance threshold for each test be ; then the probability that at least one of the tests is significant under this threshold is (1 - the probability that none of them are significant).
The following table lists values for t distributions with ν degrees of freedom for a range of one-sided or two-sided critical regions. The first column is ν , the percentages along the top are confidence levels α , {\displaystyle \ \alpha \ ,} and the numbers in the body of the table are the t α , n − 1 {\displaystyle t_{\alpha ,n-1 ...