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It is caused by cigarette smoking. [1] [2] The term SRIF was coined by Dr. Anna-Luise Katzenstein (a pathologist) and colleagues in 2010 in a study of lung specimens surgically removed for lung cancer. [3] Since then, other investigators have confirmed the same abnormality in the lungs of a subset of smokers. [4] [5]
The potential effects of smoking, such as lung cancer, can take up to 20 years to manifest themselves. Historically, women began smoking en masse later than men, so an increased death rate caused by smoking amongst women did not appear until later. The male lung cancer death rate decreased in 1975—roughly 20 years after the initial decline in ...
Smoking is a known cause of some types of lung fibrosis, such as smoking-related interstitial fibrosis (SRIF). [11] Some typical connective tissue diseases [7] such as rheumatoid arthritis, ankylosing spondylitis, SLE and scleroderma; Other diseases that involve connective tissue, such as sarcoidosis and granulomatosis with polyangiitis
Based on the CDC's statistics, the risk of developing lung cancer by smoking cigarettes increases by a factor of 23 for men and 13 for women relative to non-smokers, while five-year survival rates ...
Cigarettes are known to cause many lung diseases including emphysema, chronic bronchitis, and lung cancer. Smoker's macrophages are alveolar macrophages whose characteristics, including appearance, cellularity, phenotypes, immune response, and other functions, have been affected upon the exposure to cigarettes. [1]
Smoking tobacco causes various types and subtypes of cancers [94] (particularly lung cancer, cancers of the oropharynx, [95] larynx, [95] and mouth, [95] esophageal and pancreatic cancer). [18] Using tobacco, especially together with alcohol , is a major risk factor for head and neck cancer . 72% of head and neck cancer cases are caused by ...
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