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Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
[18] [needs update] While most people have headaches of the same type they experienced before the injury, people diagnosed with PCS often report more frequent or longer-lasting headaches. [18] Between 30% and 90% of people treated for PCS report having more frequent headaches and between 8% and 32% still report them a year after the injury.
Studies on animals have shown that the brain may be more vulnerable to a second concussive injury administered shortly after a first. [31] In one such study, a mild impact administered within 24 hours of another one with minimal neurological impairment caused massive breakdown of the blood brain barrier and subsequent brain swelling. [ 22 ]
Chronic wounds take a long time to heal and patients can experience chronic wounds for many years. [43] Chronic wound healing may be compromised by coexisting underlying conditions, such as venous valve backflow , peripheral vascular disease , uncontrolled edema and diabetes mellitus .
The fourth and final phase of wound healing, remodeling/scar formation, typically lasts 12 months but can continue as long as 2 years after the initial injury. [6] [7] Acute wounds can further be classified as either open or closed. An open wound is any injury whereby the integrity of the skin has been disrupted and the underlying tissue is ...
It involves a coordinated and systemic mobilization response locally of various immune, endocrine and neurological mediators of acute inflammation. In a normal healthy response, it becomes activated, clears the pathogen and begins a repair process and then ceases. [10] Acute inflammation occurs immediately upon injury, lasting only a few days. [11]
More severe rhabdomyolysis is characterized by muscle pain, tenderness, weakness and swelling of the affected muscles. [10] If the swelling is very rapid, as may happen with a crush injury after someone is released from under heavy collapsed debris, the movement of fluid from the bloodstream into damaged muscle may cause low blood pressure and ...
A concussion, also known as a mild traumatic brain injury (mTBI), is a head injury that temporarily affects brain functioning. [8] Symptoms may include headache, dizziness, difficulty with thinking and concentration, sleep disturbances, mood changes, a brief period of memory loss, brief loss of consciousness; problems with balance; nausea; blurred vision; and mood changes.