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Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat.
Acarbose is a starch blocker. It works by inhibiting alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates such as starch and sucrose. It is composed of an acarviosin moiety with a maltose at the reducing terminus. It can be degraded by a number of gut bacteria. [3]
If you’ve ever (over)eaten a big bowl of pasta, only to feel sleepy and lethargic a few minutes later, that’s known as a good old food coma. A blood sugar spike and subsequent crash can do ...
Anyone who says they don’t enjoy pasta, cookies and bread every once in a while (or more, of course) simply has to be lying! Yes, some people choose to avoid simple carbs and sugars for valid ...
A European Medicines Agency review concluded that there is a potential increased risk of lower limb amputation (mostly affecting the toes) in people taking canagliflozin, dapagliflozin and empagliflozin. [17] In August 2018, the FDA issued a warning of an increased risk of Fournier gangrene in patients using SGLT2 inhibitors. [18]
According to the carbohydrate–insulin model, low-carbohydrate diets would be the most effective in causing long-term weight loss. Notable proponents of the carbohydrate–insulin model include Gary Taubes and David Ludwig. [1] [2] The CIM has been tested in mice [3] and humans. [4]