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Nelson claims that relative to marijuana, products containing synthetic cannabinoids "are really quite different, and the effects are much more unpredictable. It's dangerous". [47] Since the term synthetic does not apply to the plant, but rather to the cannabinoid that the plant contains , the term synthetic cannabinoid is more appropriate. [48]
During the 1960s and 1970s, a number of new synthetic hallucinogens were introduced, with a notable example being the sale of highly potent tablets of DOM in San Francisco in 1967. [9] There was little scope to prosecute people over drug analogues at this time, with new compounds instead being added to the controlled drug schedules one by one ...
Synthetic cannabinoids act as Synthetic Cannabinoid Receptor Agonists (SCRA) [10] by binding to cannabinoid receptors CB 1 and CB 2. Its binding towards CB 1 receptor will lead to receptor phosphorylation that recruits β-arrestin 1 and β-arrestin 2, resulting in a loss of responsiveness and internalization (endocytosis of molecules by the cell).
Cannabis concentrate, also called marijuana concentrate, marijuana extract, or cannabis extract, is a tetrahydrocannabinol (THC) and/or cannabidiol (CBD) concentrated mass. Cannabis concentrates contain high THC levels that range from 40% to over 90%, [ 1 ] [ 2 ] stronger in THC content than high-grade marijuana, which normally measures around ...
APICA (2NE1, SDB-001, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide) is an indole based drug that acts as a potent agonist for the cannabinoid receptors. [1]It had never previously been reported in the scientific or patent literature, and was first identified by laboratories in Japan in March 2012 as an ingredient in synthetic cannabis smoking blends, along with its indazole derivative ...
Oct. 27—HANOVER TWP. — Three people from the same family were arrested Thursday on allegations they were peddling synthetic marijuana tainted with illicit drugs. Police in Hanover Township ...
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
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