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The intermediate mesoderm connects the paraxial mesoderm with the lateral plate mesoderm, and differentiates into urogenital structures. [12] In upper thoracic and cervical regions, this forms the nephrotomes. In caudal regions, it forms the nephrogenic cord. It also helps to develop the excretory units of the urinary system and the gonads. [4]
The reproductive organs develop from the intermediate mesoderm and are preceded by more primitive structures that are superseded before birth. These embryonic structures are the mesonephric ducts (also known as Wolffian ducts ) and the paramesonephric ducts , (also known as Müllerian ducts ).
2.2.2 Reproductive system. 2.3 Lateral plate mesoderm. 2.3.1 Hematopoietic stem cell. 2.3.2 Circulatory system. ... mesoderm, and endoderm. Cells derived from ectoderm
Intermediate mesoderm or intermediate mesenchyme is a narrow section of the mesoderm (one of the three primary germ layers) located between the paraxial mesoderm and the lateral plate of the developing embryo. [1] The intermediate mesoderm develops into vital parts of the urogenital system (kidneys, gonads and respective tracts).
The chorda-mesoderm develops into the notochord. The intermediate mesoderm develops into kidneys and gonads. The paraxial mesoderm develops into cartilage, skeletal muscle, and dermis. The lateral plate mesoderm develops into the circulatory system (including the heart and spleen), the wall of the gut, and wall of the human body. [11]
The mesonephros derives from intermediate mesoderm in the upper thoracic to upper lumbar segments. Excretory tubules are formed and enter the mesonephric duct, which ends in the cloaca. The mesonephric duct atrophies in females, but participate in development of the reproductive system in males.
The urinary and reproductive organs are developed from the intermediate mesoderm. The permanent organs of the adult are preceded by a set of structures which are purely embryonic, and which with the exception of the ducts disappear almost entirely before birth.
In the mouse gonadal primordium, the genital ridge, which forms from intermediate mesoderm, becomes morphologically distinct at E10.5. By E12, sexual differentiation of the gonad is apparent, indicating that genes involved in the formation of the bipotential gonad are expressed before E10.5 and E12.