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Simvastatin also reduced the numbers of other events like heart attacks, strokes, and revascularizations and MI significantly. [11] The Heart Protection Study evaluated the effects of simvastatin in people with risk factors including existing cardiovascular disease, diabetes, or stroke, but having relatively low LDL cholesterol. In this trial ...
Side effects of statins include muscle pain, ... In children, statins are effective at reducing cholesterol levels in those with familial hypercholesterolemia. [50]
While there have been concerns about side-effects associated with statins (myopathy and rhabdomyolysis), these were rare in this study. [citation needed] The number needed to treat in the study was 57 to postpone one death and 19 to prevent one cardiovascular "event" (in those taking the drug simvastatin for 5 years). There was no mortality ...
Sitagliptin is a dipeptidyl peptidase-4 inhibitor and simvastatin is an HMG-CoA reductase inhibitor. [1] These two disorders commonly occur in people at the same time, and have been typically treated with administration of these medications separately.
Children (1–18 years): 15 mcg or 600 IU. Adults (18–70 years): 15 mcg or 600 IU ... “Vitamin D can interact with statins, steroids and thiazide diuretics,” Zumpano says. ... Side effects ...
With median follow-up of 6 years, simvastatin+ezetimibe was found to reduce the primary outcome of CV mortality, major CV event, or nonfatal stroke (34.7% vs. 32.7%; P=0.016; NNT 50 per 7 years or NNT 350 per 1 year ). There was no reduction in all-cause or CV mortality with simvastatin+ezetimibe, though there was a reduction in MI and stroke. [6]
Dr. Michael Roizen is 78 but says his biological age is 57.6. Roizen, who has written about longevity, takes supplements every day. They include multivitamins and aspirin.
Life expectancy for U.S.-born children is now 77.5 years, up from 76.5 in 2021 and 77 in 2020. Deaths caused by drug overdoses and COVID-19 infections were key contributors to the decline, the CDC ...