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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Clindamycin was first made in 1966 from lincomycin. [11] [12] It is on the World Health Organization's List of Essential Medicines. [13] It is available as a generic medication. [14] [15] In 2022, it was the 147th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [16] [17]
Antibiotics with less reliable but occasional (depending on isolate and subspecies) activity: occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate, and piperacillin-tazobactam (not all vancomycin-resistant Enterococcus isolates are resistant to penicillin and ampicillin)
Researchers in the United States and United Kingdom have shown how the bacteria responsible for many urinary tract infections have adapted to prevent being flushed out when you pee.
Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient level, the boosted antimicrobial potency provided by synergy allows the body to more rapidly clear infections, resulting in shorter courses of antibiotic therapy. [3] Shorter courses of therapy in turn reduce the effects of dose-related toxicity, if applicable ...
Here's how E.coli and antibiotics play a part. ... Up to 60 percent of women will get a urinary tract infection (UTI) in their lifetime, making this something to at least have on your radar. But ...