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  2. List of commercially available insulins - Wikipedia

    en.wikipedia.org/wiki/List_of_commercially...

    Lente insulin (derived from the Italian word lento, meaning "slow"), also known as insulin zinc suspension, was an intermediate-acting insulin that is no longer used in humans. [87] Its effects begin one to two hours after administration, with peak activity occurring approximately 8 to 12 hours post-injection, and some residual effects lasting ...

  3. Insulin signal transduction pathway - Wikipedia

    en.wikipedia.org/wiki/Insulin_signal...

    Once insulin is synthesized, the beta cells are ready to release it in two different phases. As for the first phase, insulin release is triggered rapidly when the blood glucose level is increased. The second phase is a slow release of newly formed vesicles that are triggered regardless of the blood sugar level.

  4. Depot injection - Wikipedia

    en.wikipedia.org/wiki/Depot_injection

    Insulin glargine, for example, is designed to precipitate after injection so it can be slowly absorbed by the body over a longer period than regular insulin would be. [13] Depot injections of insulins have been studied to better replicate the body's natural basal rate of insulin production, and which can be activated by light to control the ...

  5. Insulin (medication) - Wikipedia

    en.wikipedia.org/wiki/Insulin_(medication)

    Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [85] [86] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin

  6. Insulin analogue - Wikipedia

    en.wikipedia.org/wiki/Insulin_analogue

    Zinc combinations of insulin are used for slow release of basal insulin. Basal insulin support is required throughout the day representing about 50% of daily insulin requirement, [18] the insulin amount needed at mealtime makes up for the remaining 50%. Non hexameric insulins (monomeric insulins) were developed to be faster acting and to ...

  7. Insulin glargine - Wikipedia

    en.wikipedia.org/wiki/Insulin_glargine

    After injection, microcrystals slowly release insulin for about 24 hours. [7] This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. [7] Insulin glargine was patented, but the patent expired in most jurisdictions in 2014. It was approved for medical use in the United States in 2000. [7]

  8. Are Ozempic side effects more common in females? - AOL

    www.aol.com/ozempic-side-effects-more-common...

    Ozempic side effects that are more common in females vs. males include nausea, vomiting, dizziness, and headache. ... GLP-1 medications like Ozempic directly work on the pancreas by encouraging it ...

  9. Insulin lispro - Wikipedia

    en.wikipedia.org/wiki/Insulin_lispro

    Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump .