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Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
Microsopic image of a fascial structure (Ligamentum nuchae).A fascia (/ ˈ f æ ʃ (i) ə /; pl.: fasciae / ˈ f æ ʃ i i / or fascias; [1] adjective fascial; from Latin band) is a generic term for macroscopic membranous bodily structures.
Thickened and/or tight filum terminale; Lipoma(s) in the spinal column; Dermal Sinus Tract (congenital deformity) Diastematomyelia (split spinal cord) [10] Tethered spinal cord is a disorder and not a mechanism so it does not spread to other people and there are no measures that can be done to prevent it beforehand.
H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The RGD sequence (Arg–Gly–Asp) is located in III 10 and is the site of cell attachment via α5β1 and αVβ3 integrins on the cell surface. The "synergy site" is in III 9 and has a role in modulating fibronectin's association with α5β1 integrins. [12]
The inner dense plaque, also about 15–20 nm in length, contains the C-terminus end of desmoplakin and their attachment to keratin intermediate filaments. Desmoplakin is the most abundant part of the desmosome, [7] as it operates as the mediator between the cadherin proteins in the plasma membrane and the keratin filaments. Desmoplakin has two ...
The responsible mechanism seems to be based on the inhibition of protein tyrosine phosphatase being involved in the closing process of tight junctions. [48] Due to thiolation the permeation enhancing effect of polymers such as polyacrylic acid or chitosan can be up to 10-fold improved.