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Fasciolosis is a parasitic worm infection caused by the common liver fluke Fasciola hepatica as well as by Fasciola gigantica. The disease is a plant-borne trematode zoonosis, [3] and is classified as a neglected tropical disease (NTD). [4] [5] It affects humans, but its main host is ruminants such as cattle and sheep. [4]
Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes. It infects the livers of various mammals , including humans, and is transmitted by sheep and cattle to humans all over the world.
Fasciola hepatica, a species of liver flukes, has a higher incidence rate in children and females, with more cases of lung fluke and intestinal trematodiases in children. [5] Cases of liver and lung fluke trematodiasis are frequent due to the length of time the trematode can live in host organisms, and increased chances of reinfection.
The life cycle of a typical trematode begins with an egg. Some trematode eggs hatch directly in the environment (water), while others are eaten and hatched within a host, typically a mollusc. The hatchling is called a miracidium, a free-swimming, ciliated larva. Miracidia will then grow and develop within the intermediate host into a sac-like ...
Both F. hepatica and F. gigantica and their hybrids infect the liver tissue of a wide variety of mammals, including humans, in a condition known as fascioliasis. F. hepatica measures up to 30 mm by 15 mm, while F. gigantica measures up to 75 mm by 15 mm. [2] Fasciola nyanzae is thought to exclusively infect the common hippopotamus, Hippopotamus ...
Microscopic identification of eggs, or more rarely of the adult flukes, in the stool or vomitus is the basis of specific diagnosis. The eggs are indistinguishable from those of the very closely related Fasciola hepatica liver fluke, but that is largely inconsequential since treatment is essentially identical for both.
Fasciolopsis buski is a large, dorsoventrally flattened fluke characterized by a blunt anterior end, undulating, unbranched ceca (sac-like cavities with single openings), tandem dendritic testes, branched ovaries, and ventral suckers to attach itself to the host.
Anti-viral medications are available to treat infections such as hepatitis B. [56] Other conditions may be managed by slowing down disease progression, for example: By using steroid-based drugs in autoimmune hepatitis. [57] Regularly removing a quantity of blood from a vein (venesection) in the iron overload condition, hemochromatosis. [58]