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The carotid siphon of the internal carotid artery, and cranial nerves III, IV, V (branches V 1 and V 2) and VI all pass through this blood filled space. Both sides of cavernous sinus are connected to each other via intercavernous sinuses. The cavernous sinus lies in between the inner and outer layers of dura mater. [3]
The dural venous sinuses (also called dural sinuses, cerebral sinuses, or cranial sinuses) are venous sinuses (channels) found between the periosteal and meningeal layers of dura mater in the brain. [ 1 ] [ 2 ] They receive blood from the cerebral veins , and cerebrospinal fluid (CSF) from the subarachnoid space via arachnoid granulations .
Inside the cavernous sinus, constriction of the following cranial nerves (CN) can be found: CN III (oculomotor nerve), CN IV (trochlear nerve), CN VI (abducens nerve), CN V (trigeminal nerve), specifically V1 (ophthalmic nerve) and V2 (maxillary nerve) branches. Failure of each of the nerves listed above will manifest in loss of function of the ...
The Cavernous Sinus. Each trochlear nerve originates from a trochlear nucleus in the medial midbrain.From their respective nuclei, the two trochlear nerves then travel dorsal-ward through the substance of the midbrain surrounded by the periaqueductal gray, crossing over (decussating) within the midbrain before emerging from the dorsal midbrain [3] [4] just inferior to the inferior colliculus. [4]
Medially to the trigeminal ganglion are the internal carotid artery, and the posterior part of the cavernous sinus. [2] The motor root of the trigeminal nerve passes beneath the trigeminal ganglion to exit the skull through the foramen ovale. [2] The greater petrosal nerve passes underneath the trigeminal ganglion to reach the foramen lacerum.
The abducens nerve is most likely to show signs of damage first, with the most common complaints retro-orbital pain and the involvement of cranial nerves III, IV, V1, and VI without other neurological signs or symptoms. This presentation indicates either compression of structures in the superior orbital fissure or the cavernous sinus. [citation ...
The nerve also contains fibers that innervate the intrinsic eye muscles that enable pupillary constriction and accommodation (ability to focus on near objects as in reading). The oculomotor nerve is derived from the basal plate of the embryonic midbrain. Cranial nerves IV and VI also participate in control of eye movement. [1]
Nerves may be compressed because of increased intracranial pressure, a mass effect of an intracerebral haemorrhage, or tumour that presses against the nerves and interferes with the transmission of impulses along the nerve. [22] Loss of function of a cranial nerve may sometimes be the first symptom of an intracranial or skull base cancer. [23]