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Zinc L-carnosine (beta-alanyl-L-histidinato zinc [1]) (N-(3-aminopropionyl)-L-histidinato zinc [2]), often simply called zinc carnosine, and also known as polaprezinc, [3] is a mucosal protective [4] [5] chelate compound of zinc and L-carnosine invented by Hamari Chemicals, Ltd. [6] [7] It is a quadridentate 1:1 complex of a polymeric nature. [6]
A Zn chelate supplement was compared with zinc sulfate in broiler chickens. Weight gain and feed intake increased quadratically (p<0.05) with increasing Zn concentrations from the chelate and linearly with Zn sulfate. The relative bioavailability of the Zn chelate was 183% and 157% of Zn sulfate for weight gain and tibia Zn, respectively. The ...
Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. [citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich. [1] Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine.
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Anserine is a derivative of carnosine, which has been methylated. [2] Both anserine and carnosine chelate copper. [3] Due to its methylation, anserine is more stable in serum and resistant to degradation than carnosine. [4] Anserine can be found in the skeletal muscle and brain of mammals and birds. [2]
Zinc proteinate is the final product resulting from the chelation of zinc with amino acids and/or partially hydrolyzed proteins. It is used as a nutritional animal feed supplement formulated to prevent and/or correct zinc deficiency in animals. [1] Zinc proteinate can be used in place of zinc sulfate and zinc methionine.