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The safety of the antitoxin, however, was established in a study of 40 healthy volunteers as well as in the experimental treatment of 228 patients in a CDC program. [ 11 ] After the February 2014 acquisition of Cangene Corporation by Emergent BioSolutions, Emergent took control of Cangene's products and contracts, including BAT. [ 12 ]
Caustic ingestion occurs when someone accidentally or deliberately ingests a caustic or corrosive substance.Depending on the nature of the substance, the duration of exposure and other factors it can lead to varying degrees of damage to the oral mucosa, the esophagus, and the lining of the stomach.
The Mark I NAAK (left) and its training kit (right) In the United States military, the Mark I NAAK, or MARK I Kit, ("Nerve Agent Antidote Kit") is a dual-chamber autoinjector: Two anti-nerve agent drugs—atropine sulfate and pralidoxime chloride—each in injectable form, constitute the kit.
Toxicity as blood agent Hydrogen cyanide: Colorless gas or liquid, almond odor, burns with a bluish flame. −13 / 26 °C 10 2 9 10 8 10 Cyanogen: Colorless gas, almond odor, burns with a pinkish flame having a blue border. −28 / −21 °C 9 2 9 8 7 9 Cyanogen chloride: Colorless gas or liquid, pungent and biting odor, soluble in water and ...
Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. [1] It is used to treat organophosphate poisoning [2] in conjunction with atropine and either diazepam or midazolam. It is a white solid.
In 2014, the American Association of Poison Control Centers reported about 6,000 exposures to chlorine gas in the US in 2013, compared with 13,600 exposures to carbon monoxide, which was the most common poison gas exposure; [7] the year before they reported about 5,500 cases of chlorine gas poisoning compared with around 14,300 cases of carbon ...
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
Salt poisoning is an intoxication resulting from the excessive intake of sodium (usually as sodium chloride) either in solid form or in solution (saline water, including brine, brackish water, or seawater). Salt poisoning sufficient to produce severe symptoms is rare, and lethal salt poisoning is possible but even rarer.