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Though Polysporin is marketed in the US, it holds a much smaller market share than in Canada and acts as a substitute to Johnson & Johnson's Neosporin for those allergic to the antibiotic neomycin. However, allergy to bacitracin/polymyxin B has also been reported. [2] There is also an ophthalmological ointment, eye and ear drops.
Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. [2] [3] It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. [3] It is used as an ear drop or eye drop. [2] [3]
Otitis externa, also called swimmer's ear, [1] is inflammation of the ear canal. [2] It often presents with ear pain, swelling of the ear canal, and occasionally decreased hearing. [2] Typically there is pain with movement of the outer ear. [3] A high fever is typically not present except in severe cases. [3]
A variant of Polysporin, called Polysporin Triple Ointment, replaces neomycin with gramicidin, providing an alternative for those allergic to neomycin while still offering broad-spectrum coverage against both Gram-negative and Gram-positive bacteria.
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. [1] While it is useful for many Gram negative infections, it is not useful for Gram positive infections. [1]
Ear drops should not be shared to prevent the spread of infection. [7] Ear drops should not be used after the expiration date. [7] Ear drops should only be used in the affected ear. Ear drops are usually used for a short duration of time. Make sure to only use it as prescribed. [7]
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[1] [3] They are also used externally as a cream or drops to treat otitis externa (swimmers ear), and as a component of triple antibiotic ointment to treat and prevent skin infections. [ 3 ] [ 4 ] Mechanism of action