Search results
Results From The WOW.Com Content Network
In general gene expression is regulated through changes [44] in the number and type of interactions between molecules [45] that collectively influence transcription of DNA [46] and translation of RNA. [47] Some simple examples of where gene expression is important are: Control of insulin expression so it gives a signal for blood glucose regulation.
A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses.
Regulation of gene expression, or gene regulation, [1] includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental ...
Transcription factors are proteins that bind to specific DNA sequences in order to regulate the expression of a given gene. There are approximately 1,400 transcription factors in the human genome and they constitute about 6% of all human protein coding genes. [ 21 ]
The rate of evolution is quantified as the speed of genetic or morphological change in a lineage over a period of time. The speed at which a molecular entity (such as a protein, gene, etc.) evolves is of considerable interest in evolutionary biology since determining the evolutionary rate is the first step in characterizing its evolution. [1]
The gene researchers are looking to modify (known as the gene of interest) must be separated from the extracted DNA. If the sequence is not known then a common method is to break the DNA up with a random digestion method. This is usually accomplished using restriction enzymes (enzymes that cut DNA).
The step size can also be adjusted to the smaller permissible change range depending on the current value. In any case, however, it is likely that the new value ′ of the gene will be outside the permissible range of values. Such a case must be considered a lethal mutation, since the obvious repair by using the respective violated limit as the ...
Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs once the RNA polymerase has been attached to the gene's promoter and is synthesizing the nucleotide sequence. Therefore, as the name indicates, it occurs between the transcription phase and the translation phase of gene expression. These controls are ...