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Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs.Compounds successfully developed into drugs or under research include antibiotics, anti-cancer drugs, cholesterol and ergosterol synthesis inhibitors, psychotropic drugs, immunosuppressants and fungicides.
The fungus can also exist in a carrier state on the scalp, without clinical symptomatology. Treatment of tinea capitis requires an oral antifungal agent ; griseofulvin is the most commonly used drug, but other newer antimycotic drugs, such as terbinafine , itraconazole , and fluconazole have started to gain acceptance.
The fungus was first isolated in 1870 from a tinea cruris patient in Germany by Carl Otto Harz, who named it Acrothecium floccosum. [10] Being unaware of Harz's work, Castellani and Sabouraud identified the species again in 1905 and 1907, respectively, and both placed the fungus into the genus Epidermophyton. [11]
Tullio Simoncini (1951 – May 20, 2024) is a former Italian physician known for alternative medicine advocacy. He is known for the claim that cancer is caused by the fungus Candida albicans, and has argued that cancer is a form of candida overgrowth.
The sufferers would receive ergot-free meals, wines containing vasodilating and analgesic herbs, and applications of Antonites-balsam, which was the first transdermal therapeutic system (TTS) in medical history. [25] These medical recipes have been lost to time, though some recorded treatments still remain. [29]
A fungal meningitis outbreak linked to cosmetic procedures performed at clinics in Mexico has killed four patients from the U.S. and infected over two dozen others.
Up to the mid-20th century, the mortality rate was around 60–70%, but this has been greatly reduced with advances in medical care. A review of death cap poisoning throughout Europe from 1971 to 1980 found the overall mortality rate to be 22.4% (51.3% in children under ten and 16.5% in those older than ten). [ 89 ]
Fungus is everywhere, so it's hard to avoid altogether, Garg points out. Even among people who use oral medications to treat toenail fungus, 20%-25% see a recurrence , often within two years.