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While Hurthle cells can occur in healthy thyroid glands, [1] they are often associated with Hashimoto's thyroiditis [4] and Graves' disease. [2] Hürthle cell neoplasms can be separated into Hürthle cell adenomas (benign tumours) and carcinomas (malignant tumours) [5] arising from the follicular epithelium of the thyroid gland. [6]
Hürthle cell neoplasm is a rare tumor of the thyroid, typically seen in women between the ages of 70 and 80 years old. When benign, it is called a Hürthle cell adenoma, and when malignant it is called a Hürthle cell carcinoma. Hürthle cell adenoma is characterized by a mass of benign Hürthle cells (Askanazy cells). [1]
Thyroid follicular adenoma ranges in diameter from 3 cm on an average, but sometimes is larger (up to 10 cm) or smaller. The typical thyroid adenoma is solitary, spherical and encapsulated lesion that is well demarcated from the surrounding parenchyma. The color ranges from gray-white to red-brown, depending upon the cellularity of the adenoma
Hurthle cell thyroid cancer is often considered a variant of follicular cell carcinoma. [3] [4] Hurthle cell forms are more likely than follicular carcinomas to be bilateral and multifocal and to metastasize to lymph nodes. Like follicular carcinoma, unilateral hemithyroidectomy is performed for non-invasive disease, and total thyroidectomy for ...
Thyroid cancer is cancer that develops from the tissues of the thyroid gland. [1] It is a disease in which cells grow abnormally and have the potential to spread to other parts of the body . [ 8 ] [ 9 ] Symptoms can include swelling or a lump in the neck , difficulty swallowing or voice changes including hoarseness, or a feeling of something ...
Metastatic carcinomas in the thyroid gland. Thyroid metastasis from lung adenocarcinoma (a, b). Some metastatic tumor cells (right) are positive for thyroglobulin due to diffusion artifact and should not be overinterpreted as positive (b). Metastatic clear cell renal carcinoma (c), metastatic renal cells are negative for thyroglobulin (d).