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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
Pemphigus foliaceus in dogs: hair loss occurs, skin becomes red, and itchy. Dogs suffering from autoimmune diseases of the skin may experience a variety of symptoms, including persistent itching and scratching, lesions, wounds, blisters, and other skin damage, as well as loss of skin pigment . [ 5 ]
The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or secondary (due to scratching, itch) in nature, making diagnosis complicated.
pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial; praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions
Dogs are unable to metabolize theobromine effectively. If they eat chocolate, the theobromine can remain in their bloodstreams for days, and dogs may experience fast heart rate, severe diarrhea, epileptic seizures, heart attacks, internal bleeding, and eventually death. [37]
More than 3,600 cases of debilitating dog health problems caused by the medication were reported between January 2023 and March 2024, the FDA said in the cautionary letter, published Monday.