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n/a Ensembl ENSG00000274734 ENSG00000286139 ENSG00000285077 n/a UniProt Q3KRB8 n/a RefSeq (mRNA) NM_001039841 n/a RefSeq (protein) NP_001034930 n/a Location (UCSC) Chr 15: 30.62 – 30.65 Mb n/a PubMed search n/a Wikidata View/Edit Human ARHGAP11B is a human-specific gene that amplifies basal progenitors, controls neural progenitor proliferation, and contributes to neocortex folding. It is ...
There are two types of 11β-Hydroxysteroid dehydrogenases that control cortisol concentration: HSD-11β Type 1 and HSD-11β Type 2. [9] HSD-11β Type 1 is responsible for converting cortisone to cortisol by acting as an oxo-reductase because it is NADP(H) dependent, while HSD-11β Type 2 inactivates cortisol to cortisone via NAD.
16409 Ensembl ENSG00000169896 ENSMUSG00000030786 UniProt P11215 P05555 RefSeq (mRNA) NM_000632 NM_001145808 NM_001082960 NM_008401 RefSeq (protein) NP_000623 NP_001139280 n/a Location (UCSC) Chr 16: 31.26 – 31.33 Mb Chr 7: 127.66 – 127.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta ...
11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors.
Steroid 11β-hydroxylase, also known as steroid 11β-monooxygenase, is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex.Named officially the cytochrome P450 11B1, mitochondrial, it is a protein that in humans is encoded by the CYP11B1 gene.
19326 Ensembl ENSG00000185236 ENSMUSG00000077450 UniProt Q15907 P46638 RefSeq (mRNA) NM_004218 NM_008997 RefSeq (protein) NP_004209 NP_033023 Location (UCSC) Chr 19: 8.39 – 8.4 Mb Chr 17: 33.96 – 33.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. Rab11b is reported as most abundantly ...
The structure of cocaine with relevant structural motifs for activity at the dopamine transporter highlighted. While it was originally thought that the 2β-carbomethoxy moiety interacted with the DAT through hydrogen bonding, subsequent research has indicated that electrostatic (ionic) interactions are the primary means of interactions with the DAT.
10407 546038 Ensembl ENSG00000164871 ENSG00000274405 ENSG00000288309 ENSMUSG00000059463 UniProt Q08648 Q6PDA7 Q8K4N2 Q3UW43 RefSeq (mRNA) NM_016512 NM_058200 NM_058201 NM_058202 NM_058203 NM_058206 NM_058207 NM_001034905 NM_001039563 NM_001286493 RefSeq (protein) NP_057596 NP_478107 NP_478108 NP_478109 NP_478110 NP_478113 NP_478114 NP_001075021 NP_001350655 NP_001075021 NP_001350655 NP_694755 ...