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  2. Felty's syndrome - Wikipedia

    en.wikipedia.org/wiki/Felty's_syndrome

    Felty's syndrome is also characterized by an abnormally enlarged spleen (splenomegaly) and abnormally low levels of certain white blood cells (neutropenia). As a result of neutropenia, affected individuals are increasingly susceptible to certain infections. Keratoconjunctivitis sicca may occur due to secondary Sjögren's syndrome. Individuals ...

  3. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  4. List of ICD-9 codes 280–289: diseases of the blood and blood ...

    en.wikipedia.org/wiki/List_of_ICD-9_codes_280...

    289.5 Other diseases of spleen. 289.50 Disease of spleen unspecified; 289.51 Chronic congestive splenomegaly; 289.52 Splenic sequestration; 289.53 Neutropenic splenomegaly; 289.59 Other diseases of spleen; 289.6 Familial polycythemia; 289.7 Methemoglobinemia; 289.8 Other specified diseases of blood and blood-forming organs 289.81 Primary ...

  5. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease

  6. RAS-associated autoimmune leukoproliferative disorder

    en.wikipedia.org/wiki/RAS-associated_autoimmune...

    Clinically, RALD is characterized by splenomegaly, a relatively mild degree of peripheral lymphadenopathy, and autoimmunity. The autoimmune phenotype can present in childhood or adulthood and primarily includes autoimmune hemolytic anemia, ITP, and neutropenia. Some patients have a history of recurrent respiratory tract infections.

  7. List of medical triads, tetrads, and pentads - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_triads...

    Rheumatoid arthritis, neutropenia, splenomegaly: Rheumatoid arthritis complication: Goodpasture syndrome Triad: Glomerulonephritis, pulmonary hemorrhage, presence of anti-GBM antibodies: Goodpasture syndrome: Gradenigos Triad: Sixth cranial n. Palsy, Persistent ear discharge, Deep seated retro orbital pain: Gradenigo's syndrome: Graves Disease ...

  8. Gaucher's disease - Wikipedia

    en.wikipedia.org/wiki/Gaucher's_disease

    Splenomegaly may decrease the affected individual's capacity for eating by exerting pressure on the stomach. While painless, enlargement of the spleen increases the risk of splenic rupture. Hypersplenism and pancytopenia , the rapid and premature destruction of blood cells, leads to anemia , neutropenia , leukopenia , and thrombocytopenia (with ...

  9. Agranulocytosis - Wikipedia

    en.wikipedia.org/wiki/Agranulocytosis

    Neutropenia indicates a deficiency of neutrophils (the most common granulocyte cell) only. [citation needed] To be precise, neutropenia is the term normally used to describe absolute neutrophil counts (ANCs) of less than 500 cells per microlitre, whereas agranulocytosis is reserved for cases with ANCs of less than 100 cells per microlitre.