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Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [2] [8] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a lower than normal number of red blood cells, due to a deficiency of vitamin B 12. [ 5 ] [ 16 ] The ability to absorb the vitamin declines with age, especially in people over 60.
However, in people who have the autoimmune disease pernicious anemia, antibodies bind to the intrinsic factor, ... Vitamin B-12 1,000 mcg with Folic Acid. amazon.com. $14.38. Raw B-12. Shop Now.
That includes folks with an autoimmune disorder called pernicious anemia, who are unable to absorb B12, and people who take a lot of over-the-counter stomach-acid reducers, like famotidine ...
Pernicious anemia [35] is a form of megaloblastic anemia due to vitamin B 12 deficiency dependent on impaired absorption of vitamin B 12. Lack of dietary B 12 causes non-pernicious megaloblastic anemia. Anemia of folate deficiency, [35] as with vitamin B 12, causes megaloblastic anemia