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Potassium bromide (K Br) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US. Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide is used as a veterinary drug, in antiepileptic medication for dogs.
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Bromide is so soluble that it does not form saline minerals. After halite (rock salt) precipitates, the remaining brine, called bittern, contains about 2,700 ppm bromine. Bromine continues to concentrate as magnesium and potassium minerals precipitate. The brine remaining after potassium mineral precipitation may contain 6,000 ppm bromine. [1]
Potassium bromate is typically used in the United States as a flour improver (E number E924). It acts to strengthen the dough and to allow higher rising. It is an oxidizing agent, and under the right conditions, is reduced to bromide in the baking process.
Bromide compounds, especially potassium bromide, were frequently used as sedatives in the 19th and early 20th centuries. Their use in over-the-counter sedatives and headache remedies (such as Bromo-Seltzer ) in the United States extended to 1975 when bromides were withdrawn as ingredients due to chronic toxicity . [ 14 ]
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Bromism is the syndrome which results from the long-term consumption of bromine, usually through bromine-based sedatives such as potassium bromide and lithium bromide. Bromism was once a very common disorder, being responsible for 5 to 10% of psychiatric hospital admissions, but is now uncommon since bromide was withdrawn from clinical use in ...
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