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The bromelain gel is contraindicated in persons allergic to pineapple or the enzyme papain. [3] The most common side-effects are fever (19% of patients in studies) and local pain (3.6%). Wound infections occur no more frequently than under standard treatment. [3]
Bromelain is an enzyme extract derived from the stems of pineapples, although it exists in all parts of the fresh plant and fruit. The extract has a history of folk medicine use. As a culinary ingredient, it may be used as a meat tenderizer .
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Adverse effects include a transient increase in serum glucose level, and poor wound healing (controversial). Medications include dexamethasone. Butyrophenones are typically administered as a single injection at the end of surgery. Adverse effects include prolongation of the QT interval on EKG. Medications include droperidol and haloperidol.
Amnesia is desirable during surgery, so general anaesthesia procedures are designed to induce it for the duration of the operation. Sedatives such as benzodiazepines, which are commonly used for anxiety disorders, can reduce the encoding of new memories, particularly in high doses (for example, prior to surgery in order for a person not to recall the surgery). [2]
It is thought that it may be caused by the body's inflammatory response to surgery, stress hormone release during surgery, ischemia, or hypoxaemia. [5] [6] Post-operative cognitive dysfunction can complicate a person's recovery from surgery, delay discharge from hospital, delay returning to work following surgery, and reduce a person's quality ...
The therapeutic benefit against asthenia was observed to still be present one month after discontinuation of the drug. [7] 3% of patients experienced side effects; though none were considered serious; and 0.8% of patients discontinued treatment due to side effects. [7] Bromantane was also noted to normalize the sleep-wake cycle. [7]
The authors concluded patients with long-standing coronary artery disease have some degree of cognitive dysfunction secondary to cerebrovascular disease before surgery; there is no evidence the cognitive test performance of bypass surgery patients differed from similar control groups with coronary artery disease over a 12-month follow-up period.