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Splenic marginal zone lymphoma (SMZL) is a type of marginal zone lymphoma, a cancer made up of B-cells that replace the normal architecture of the white pulp of the spleen. The neoplastic cells are both small lymphocytes and larger, transformed lymphoblasts , and they invade the mantle zone of splenic follicles and erode the marginal zone ...
Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...
Hemangiosarcoma of the spleen or liver is the most common tumor to cause hemorrhage in the abdomen. [4] Hemorrhage secondary to splenic and hepatic tumors can also cause ventricular arrhythmias . Hemangiosarcoma of the skin usually appears as a small red or bluish-black lump.
The cell of origin for this disease is an immature cytotoxic T-cell clonally expressing the γδ T-cell receptor.The disease is seen more often in immunosuppressed recipients of solid organ transplants, an association that has led to the hypothesis that long-term immune stimulation in the setting of immunosuppression is the causative agent.
Accessory spleens may undergo hypertrophy after splenectomy [15] Very rarely, it may cause bleeding (pictured). [16]If splenectomy is performed for conditions in which blood cells are sequestered in the spleen, failure to remove accessory spleens may result in the failure of the condition to resolve. [1]
While it's possible to live without organs like the appendix, gallbladder, or spleen, several of our organs are considered especially vital for survival. These include the brain, heart, lungs ...
Splenomegaly can result in hematologic disturbances and abdominal pain and can increase the risk for splenic rupture, which also causes spleen pain, from blunt trauma, resulting in life-threatening internal bleeding. [2] Many conditions can cause splenomegaly, such as various infections, liver disease, and cancer. [2]