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Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. [ 1 ] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to ...
Elixir sulfanilamide was an improperly prepared sulfonamide antibiotic that caused mass poisoning in the United States in 1937. It is believed to have killed 107 people. [ 1 ] The public outcry caused by this incident and other similar disasters led to the passing of the 1938 Federal Food, Drug, and Cosmetic Act , which significantly increased ...
Sulfonamide functional group Hydrochlorothiazide is a sulfonamide and a thiazide. Furosemide is a sulfonamide, but not a thiazide. Sulfamethoxazole is an antibacterial sulfonamide. Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs.
Pages in category "Sulfonamide antibiotics" The following 42 pages are in this category, out of 42 total. This list may not reflect recent changes. *
The review found that "Most of the studies evaluating prenatal exposure observed a negative effect on mental development and an increase in attention problems in preschool and school children." [30] In 2017, a study looked at the possible effects of agricultural pesticides in over 500,000 births in a largely agricultural region of California ...
The structure of the sulfonamide group. In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure R−S(=O) 2 −NR 2. It consists of a sulfonyl group (O=S=O) connected to an amine group (−NH 2). Relatively speaking this group is unreactive.
Sulfonamide hypersensitivity syndrome is similar to anticonvulsant hypersensitivity syndrome, but the onset is often sooner in the treatment course, generally after 7–14 days of therapy. [ 1 ] : 118–9
Antimicrobial use has been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. [5]In the 19th century, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism between some bacteria and discussed the merits of controlling these interactions in medicine. [6]