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Recent studies have used fMRI to explore specific brain networks, such as the salience network and default mode network, to understand their roles in schizophrenia-related symptoms. Alterations in these networks may affect self-referential thoughts and responses to external stimuli, potentially contributing to symptoms like hallucinations and ...
The parahippocampal gyrus (or hippocampal gyrus [1]) is a grey matter cortical region of the brain that surrounds the hippocampus and is part of the limbic system. The region plays an important role in memory encoding and retrieval. It has been involved in some cases of hippocampal sclerosis. [2] Asymmetry has been observed in schizophrenia. [3]
Raichle coined the term "default mode" in 2001 to describe resting state brain function; [19] the concept rapidly became a central theme in neuroscience. [20] Around this time the idea was developed that this network of brain areas is involved in internally directed thoughts and is suspended during specific goal-directed behaviors.
Abnormal activity in the PCC has been linked to schizophrenia, a mental disorder with common symptoms such as hallucinations, delusions, disorganized thinking, and a lack of emotional intelligence. What is common between symptoms is that they have to do with an inability to distinguish between internal and external events.
schizophrenia; Nigrostriatal pathway: The nigrostriatal pathway transmits dopaminergic neurons from the zona compacta of the substantia nigra [8] to the caudate nucleus and putamen. The substantia nigra is located in the midbrain, while both the caudate nucleus and putamen are located in the dorsal striatum. motor function; reward-related cognition
Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7] Symptoms develop gradually and typically begin during young adulthood and are never resolved.
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