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Neuropathic pain has profound physiological effects on the brain which can manifest as psychological disorders. Rodent models where the social effects of chronic pain can be isolated from other factors suggest that induction of chronic pain can cause anxio-depressive symptoms and that particular circuits in the brain have a direct connection.
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
From a stimulus-response perspective, the perception of physical pain starts with the nociceptors, a type of physiological receptor that transmits neural signals to the brain when activated. These receptors are commonly found in the skin, membranes, deep fascias, mucosa, connective tissues of visceral organs, ligaments and articular capsules ...
Memory lapses can be both aggravating and frustrating but they are due to the overwhelming number of information that is being taken in by the brain. Issues in memory can also be linked to several common physical and psychological causes, such as: anxiety, dehydration, depression, infections, medication side effects, poor nutrition, vitamin B12 ...
The physiological effects of chronic stress can negatively affect memory and learning. [19] One study used rats to show the effects of chronic stress on memory by exposing them to a cat for five weeks and being randomly assigned to a different group each day. [20]
The theory offered a physiological explanation for the previously observed effect of psychology on pain perception. [ 10 ] In 1968, three years after the introduction of the gate control theory, Ronald Melzack concluded that pain is a multidimensional complex with numerous sensory, affective, cognitive, and evaluative components.
Peripheral neuropathy is associated with a sensory loss in a "glove and stocking" distribution that begins at the peripheral and slowly progresses upwards, and may also be associated with acute and chronic pain. Peripheral neuropathy is not just limited to the somatosensory nerves, but the autonomic nervous system too (autonomic neuropathy). [8]
Body memory (BM) is a hypothesis that the body itself is capable of storing memories, as opposed to only the brain. While experiments have demonstrated the possibility of cellular memory [1] there are currently no known means by which tissues other than the brain would be capable of storing memories. [2] [3]