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It was founded in 2002 by Kimber Wakefield MacGibbon, [2] Ann Marie King, [3] and Jeremy King. [4] The Foundation’s main goals are (1) to minimize the suffering and complications related to HG through education, (2) to develop an effective HG treatment protocol, (3) to eliminate the need to terminate pregnancy due to ineffective HG treatment ...
The index case or patient zero is the first documented patient in a disease epidemic within a population, [1] or the first documented patient included in an epidemiological study. [2] It can also refer to the first case of a condition or syndrome (not necessarily contagious) to be described in the medical literature, whether or not the patient ...
For example, morning sickness is a fairly common mild symptom of pregnancy that generally resolves in the second trimester, but hyperemesis gravidarum is a severe form of this symptom that sometimes requires medical intervention to prevent electrolyte imbalances from severe vomiting.
Hyperemesis gravidarum (HG) is a pregnancy complication that is characterized by severe nausea, vomiting, weight loss, and possibly dehydration. [1] Feeling faint may also occur. [2] It is considered a more severe form of morning sickness. [2] Symptoms often get better after the 20th week of pregnancy but may last the entire pregnancy duration.
The chemoreceptor trigger zone at the base of the fourth ventricle has numerous dopamine D 2 receptors, serotonin 5-HT 3 receptors, opioid receptors, acetylcholine receptors, and receptors for substance P. Stimulation of different receptors are involved in different pathways leading to emesis, in the final common pathway substance P appears ...
Ovarian hyperstimulation syndrome is particularly associated with injection of a hormone called human chorionic gonadotropin (hCG) which is used for inducing final oocyte maturation and/or triggering oocyte release. The risk is further increased by multiple doses of hCG after ovulation and if the procedure results in pregnancy. [2]
Tropisetron (Setrovel, Navoban) can be administered in oral capsules or in injection form. Palonosetron ( Aloxi ) can be administered in an injection or in oral capsules. Dopamine antagonists act on the brainstem and are used to treat nausea and vomiting associated with cancer , radiation sickness, opioids, cytotoxic drugs and general anaesthetics.
Recovery phase is typically the phase where vomiting ceases, nausea diminishes or is absent, and appetite returns. "Cyclic vomiting syndrome (CVS) is a rare abnormality of the neuroendocrine system that affects 2% of children." [1] This disorder is thought to be closely related to migraines and family history of migraines. [2] [3]