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Friedrich Urech synthesized 5-methylhydantoin in 1873 from alanine sulfate and potassium cyanate in what is now known as the Urech hydantoin synthesis. [2] The method is very similar to the modern route using alkyl and arylcyanates.
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
The reason some dogs develop kidney failure following ingestion of grapes and raisins is not known. [3] Types of grapes involved include both seedless and seeded, store-bought and homegrown, and grape pressings from wineries. [4] A mycotoxin is suspected to be involved, but none has been found in grapes or raisins ingested by affected dogs. [5]
This is a collection of articles about the health and care of dogs, primarily domestic dogs. This includes medical conditions, health issues, parasites, surgical procedures, and similar topics. The main article for this category is Dog health .
Although a small preliminary study [54] indicated xylitol may be safe for dogs, other studies show significant toxicity. [55] There have been cases of foods, candies and gums containing xylitol causing toxic or even fatal liver damage in dogs. [56] [57] [58] Ingestion may cause hypoglycemia. [38]
The first recalls were announced by Menu Foods late on Friday, 16 March 2007, for cat and dog food products in the United States. In the ensuing months, many additional recalls were announced by Menu and other companies as the recall expanded throughout North America and to Europe and South Africa.
Katy Perry is leaving American Idol in good hands.. After the "Dark Horse" singer announced that season 22 of the singing competition show would be her last in February 2024, fans wondered who ...
Additionally, chronic toxicity tests tend to require significantly more attention and resources than acute tests which makes them much less feasible for basing decisions off of in a timely manner. The need for development of more advanced statistical methods, and uniformity in using these methods by regulators has been made apparent in literature.