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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Chemotherapy-induced hyperpigmentation is caused by many chemotherapeutic agents (especially the antibiotics bleomycin, and daunorubicin) and the alkylating agents (cyclophosphamide and busulfan). [ 1 ] : 132
Chemotherapy-induced acral erythema (palmoplantar erythrodysesthesia syndrome) Chemotherapy-induced hyperpigmentation; Drug-induced acne; Drug-induced angioedema; Drug-related gingival hyperplasia; Drug-induced lichenoid reaction (drug-induced lichen planus, lichenoid drug eruption) Drug-induced lupus erythematosus; Drug-induced nail changes
Acral melanoma, in particular, is a subset of melanoma that grows on the palms and soles. People with darker skin tones are particularly at risk for this type of skin cancer, says Berry. It’s ...
As of yet, the precise etiology of necrolytic acral erythema remains unknown. Numerous causes, including hepatic dysfunction, hypoglucagonemia, hypoalbimunemia, hypoaminoacidemia, zinc deficiency, and diabetes with or without an underlying hepatitis C viral infection, have been postulated as part of the multifactorial pathophysiology of necrolytic acral erythema.
Chemotherapy-induced acral erythema; D. Deep gyrate erythema; E. Erythema annulare centrifugum; Erythema chronicum migrans; Erythema gyratum repens; Erythema marginatum;