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Meropenem, imipenem-cilastatin, or ertapenem are preferred agents; ertapenem offers a more convenient option for patients needing to continue carbapenem therapy in the outpatient setting when oral treatment options are not available.
Suggested approach: Meropenem, imipenem-cilastatin, or ertapenem are preferred for the treatment of infections outside of the urinary tract caused by ESBL-E. For patients who are critically ill and/or experiencing hypoalbuminemia, meropenem or imipenem-cilastatin are the preferred carbapenems.
In June 2010, the Clinical and Laboratory Standards Institute (CLSI) published new MIC and disk diffusion interpretive criteria (i.e., breakpoints) for the Enterobacteriaceae for five cephalosporins, including: and for three carbapenems (imipenem, meropenem, and ertapenem).
Hospitalization and empiric antibacterial therapy with vancomycin plus antipseudomonal antibiotics such as cefepime, a carbapenem (imipenem-cilastatin or meropenem or doripenem) or piperacillin-tazobactam is recommended (strong, high).
Ertapenem (1g q24) ... ≤1 2 ≥4 ≤4 8 ≥16 ≥23 20-22 ≤19 ≥16 14-15 ≤13 Meropenem (1g q8) ≤1 2 ≥4 ≤4 8 ≥16 ≥23 20-22 ≤19 ≥16 14-15 ≤13 † S, susceptible; l, intermediate; R, resistant ‡ Dosage used to establish breakpoints *NA, not applicable Reference ...
Vancomycin plus an anti-pseudomonal beta-lactam (such as cefepime, ceftazidime, or meropenem) is recommended as empiric therapy for healthcare-associated ventriculitis and meningitis; the choice of empiric beta-lactam agent should be based on local in vitro susceptibility patterns (strong, low).
Native Vertebral Osteomyelitis; NVO; antimicrobial therapy These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO).
IDSA Home
Outpatient and Home Infusion Therapy: List of Codes. With some insurance carriers, you will need to add modifier -59 to the pushes and/or infusion supplies code. * Home Infusion Therapy, antibiotic, antiviral, or antifungal therapy; administrative services, professional pharmacy services, care coordination, and all necessary supplies and ...
A urine culture grew Klebsiella pneumoniae resistant to meropenem, ertapenem, nitrofurantoin, TMP/SMX, and ciprofloxacin. a. Indicate which antibiotic you would most realistically choose to treat this patient with cystitis, assuming susceptibility to all of the following (colistin MIC≤2 mcg/ml (I)):