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Drug expiration. Drug expiration is the date after which a drug might not be suitable for use as manufactured. Consumers can determine the shelf life for a drug by checking its pharmaceutical packaging for an expiration date. Drugs which are past their shelf life can decompose [1] and either be ineffective [2] or even harmful. [2]
Shelf Life Extension Program. To reduce the cost to the military of maintaining stockpiles of certain pharmaceuticals, the United States Department of Defense and the Food and Drug Administration operate a joint initiative known as the Shelf-Life Extension Program (SLEP), which evaluates the long-term effectiveness of medications stockpiled by ...
Diazepam. Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [14]
This helps keep the arteries clear so blood has an easier way of traveling throughout the body. ... their quality-adjusted life years by 0.24-0.70, and those on higher-intensity statin therapy ...
Elimination rate constant. The elimination rate constant K or Ke is a value used in pharmacokinetics to describe the rate at which a drug is removed from the human system. [1] It is often abbreviated K or Ke. It is equivalent to the fraction of a substance that is removed per unit time measured at any particular instant and has units of T −1.
“It’s important to study women to find out how to care for [51%] of the population. We are the majority of the population. So, although women are special, we are not a ‘special population.’”
Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (C max) to half of C max in the blood plasma. [1][2][3][4][5] It is denoted by the abbreviation . [2][4] This is used to measure the removal of ...
A V D greater than the total volume of body water (approximately 42 liters in humans [5]) is possible, and would indicate that the drug is highly distributed into tissue. In other words, the volume of distribution is smaller in the drug staying in the plasma than that of a drug that is widely distributed in tissues. [6]