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Atopy is a hereditary [3] and chronic (lifelong) allergic skin disease. Signs usually begin between 6 months and 3 years of age, with some breeds of dog, such as the golden retriever, showing signs at an earlier age. Dogs with atopic dermatitis are itchy, especially around the eyes, muzzle, ears and feet. In severe cases, the irritation is ...
Thymus hyperplasia refers to an enlargement ("hyperplasia") of the thymus. [1] It is not always a disease state. The size of the thymus usually peaks during adolescence and atrophies in the following decades. Before the immune function of the thymus was well understood, the enlargement was sometimes seen as a cause for alarm, and justification ...
Autoimmune skin diseases occur when the immune system of an infected animal attacks its own skin. [1] In dogs, autoimmune skin diseases are usually not detected until visible symptoms appear, which differs from detection in humans who are able to verbally express their concerns. [2] Genetics, nutrition, and external environmental factors all ...
The thymus (pl.: thymuses or thymi) is a specialized primary lymphoid organ of the immune system. Within the thymus, thymus cell lymphocytes or T cells mature. T cells are critical to the adaptive immune system, where the body adapts to specific foreign invaders. The thymus is located in the upper front part of the chest, in the anterior ...
Extramedullary hematopoiesis. Micrograph showing nucleated red blood cells (bottom left of image), one of the elements necessary to call extramedullary hematopoiesis, in an endometrial polyp. H&E stain. Extramedullary hematopoiesis (EMH or sometimes EH[1]) refers to hematopoiesis occurring outside of the medulla of the bone (bone marrow). [2]
Thymoma. surgical removal, chemotherapy (in malignant cases). A thymoma is a tumor originating from the epithelial cells of the thymus that is considered a rare neoplasm. [1] Thymomas are frequently associated with neuromuscular disorders such as myasthenia gravis; [2] thymoma is found in 20% of patients with myasthenia gravis. [3]
Symptoms. Canine discoid lupus erythematosus showing loss of noseprint, depigmentation, ulceration and tissue destruction - all characteristic of the syndrome. The most common initial symptom is scaling and loss of pigment on the nose. The surface of the nose becomes smooth gray, and ulcerated, instead of the normal black cobblestone texture.
Multiple Endocrine Neoplasia type 1 (MEN1) is a rare hereditary endocrine cancer syndrome characterized primarily by tumors of the parathyroid glands (95% of cases), endocrine gastroenteropancreatic (GEP) tract (30–80% of cases), and anterior pituitary (15–90% of cases). [19] Other endocrine and non-endocrine neoplasms including ...