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Older adults with schizophrenia are prone to extrapyramidal side effects, anticholinergic toxicity, and sedation due to increased body fat, decreased total body water, and decreased muscle mass. [ 24 ] [ 25 ] Older adults with late-onset schizophrenia usually take half of the typical dose for older adults with early-onset schizophrenia.
Schizophrenia is a neurodevelopmental disorder with no precise or single cause. Schizophrenia is thought to arise from multiple mechanisms and complex gene–environment interactions with vulnerability factors. [1][2] Risk factors of schizophrenia have been identified and include genetic factors, environmental factors such as experiences in ...
Schizophrenia was the last diagnosis to benefit from the link made between ACEs and adult mental health outcomes. [ 109 ] Living in an urban environment during childhood or as an adult has consistently been found to increase the risk of schizophrenia by a factor of two, [ 27 ] [ 110 ] even after taking into account drug use , ethnic group , and ...
The diagnosis of schizophrenia, a psychotic disorder, is based on criteria in either the American Psychiatric Association 's Diagnostic and Statistical Manual of Mental Disorders, or the World Health Organization 's International Classification of Diseases (ICD). [1] Clinical assessment of schizophrenia is carried out by a mental health ...
By age and gender. Schizophrenia is diagnosed 1.4 times more frequently in males than females, and typically appears earlier in men [ 7 ] —the peak ages of onset are 20–28 years for males and 26–32 years for females. [ 9 ] Onset in childhood, before the age of 13 can sometimes occur. [ 10 ][ 11 ] A later onset can occur between the ages ...
Genain quadruplets. The Genain quadruplets (born in 1930) are a set of identical quadruplet sisters. All four developed schizophrenia, suggesting a large genetic component to the cause of the disease. [1] The pseudonym Genain, used to protect the identity of the family, comes from the Greek, meaning dire (αἶνος) birth (γεν-). [1]
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