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Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
One current theory of the pathophysiology of ASD is that it arises from a deficit in the folate-methionine pathway. [36] Folate donates methyl groups to convert homocysteine into methionine, which is the precursor of S-adenosylmethionine. S-adenosylmethionine is the methyl group donor responsible for DNA and histone methylation. [37]
Critical autism studies (CAS) is an interdisciplinary research field within autism studies led by autistic people. [1] [2] [3] This field is related to both disability studies and neurodiversity studies. [4] [5] [6] CAS as a discipline is led by autistic academics, and many autistic people engage with the discipline in nonacademic spaces.
The Autism Informatics Consortium (AIC) was launched in 2011 with the goal of accelerating scientific discovery by making informatics tools and resources more useful to autism researchers. Current members include Autism Speaks, Kennedy Krieger Institute, Simons Foundation, Prometheus Research, and the NIH. [5]
ASD (autism spectrum disorder) is a neurodevelopmental disorder marked by impairments in communicative ability and social interaction, as well as restricted and repetitive behaviors, interests, or activities not suitable for the individual's developmental stage. The severity of symptoms and functional impairment vary between individuals. [3]
Autism Research is a bimonthly peer-reviewed medical journal covering research on autism and other pervasive developmental disorders. It was established in 2008 and is the official journal of the International Society for Autism Research. It is published bimonthly by Wiley-Blackwell. The editor-in-chief is David G. Amaral (University of ...