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  2. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    The spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic checkpoint, is a cell cycle checkpoint during metaphase of mitosis or meiosis that prevents the separation of the duplicated chromosomes until each chromosome is properly attached to the ...

  3. Metaphase - Wikipedia

    en.wikipedia.org/wiki/Metaphase

    Metaphase (from Ancient Greek μετα- beyond, above, transcending and from Ancient Greek φάσις (phásis) 'appearance') is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase). [1]

  4. Cell cycle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle_checkpoint

    Rb without a phosphate, or unphosphorylated Rb, regulates G0 cell cycle exit and differentiation. During the beginning of the G1 phase, growth factors and DNA damage signal for the rise of cyclin D levels, which then binds to Cdk4 and Cdk6 to form the CyclinD:Cdk4/6 complex. [11] This complex is known to inactivate Rb by phosphorylation.

  5. Spindle apparatus - Wikipedia

    en.wikipedia.org/wiki/Spindle_apparatus

    Micrograph showing condensed chromosomes in blue, kinetochores in pink, and microtubules in green during metaphase of mitosis. In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.

  6. Multipolar spindles - Wikipedia

    en.wikipedia.org/wiki/Multipolar_spindles

    The presence of multipolar spindles in cancer cells is one of many differences from normal cells which can be seen under a microscope.Cancer is defined by uncontrolled cell growth and malignant cells can undergo cell division with multipolar spindles because they can group multiple centrosomes into two spindles.

  7. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    A primitive form of cell division, called amitosis, also exists. The amitotic or mitotic cell divisions are more atypical and diverse among the various groups of organisms, such as protists (namely diatoms, dinoflagellates, etc.) and fungi. [citation needed]

  8. Cytogenetics - Wikipedia

    en.wikipedia.org/wiki/Cytogenetics

    A metaphase cell positive for the BCR/ABL rearrangement using FISH. Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology (a subdivision of human anatomy), that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour during mitosis and meiosis. [1]

  9. Aster (cell biology) - Wikipedia

    en.wikipedia.org/wiki/Aster_(cell_biology)

    At the negative ends of the aster centrosomes will nucleate (form a nucleus) and anchor to the microtubules. At the positive end, polymerization of the aster will occur. Cortical dynein, a motor protein, moves along the microtubules of the cell and plays a key role in the growth and inhibition of aster microtubules.