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Spironolactone can cause breast pain and breast enlargement in women. [ 128 ] [ 129 ] This is "probably because of estrogenic effects on target tissue." [ 111 ] At low doses, breast tenderness has been reported in only 5% of women, but at high doses, it has been reported in up to 40% of women.
Certain side effects, like breast enlargement, reduced premenstrual symptoms, and less oily skin/greasy hair, could be beneficial. Side effects often could not be unambiguously attributed to spironolactone due concomitant use of other medications, particularly birth control pills .
Breast pain that is not linked to a menstrual cycle is called noncyclic breast pain. Noncyclical breast pain has various causes and is harder to diagnose and frequently the root cause is outside the breast. Some degree of non-cyclical breast tenderness can normally be present due to hormonal changes in puberty (both in girls and boys), in ...
It can cause a range of potential symptoms, including chest pain that can feel like pressure, tightness, pain, squeezing, or aching, as well as fatigue, nausea, and shortness of breath. A heart ...
However, a small clinical study found that high doses of spironolactone had neither progestogenic nor antiprogestogenic effects in women. [16] [17] In any case, if one or both of these actions are clinically relevant, they might contribute to the menstrual irregularities and breast side effects of spironolactone.
Woman experiencing breast pain Breast cancer is the most common cancer in women besides skin cancer. According to the American Cancer Society , the disease accounts for about 30 percent of new ...
Some types of breast pain are normal—but others could signify a larger issue. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways ...
Through their ability to cause amenorrhea, progestogen-only pills can help reduce the symptoms associated with this condition. Levonorgestrel-IUDs may be more effective than progestogen-only pills and reducing associated bleeding (maintaining healthy hemoglobin levels), uterine volume, and pain, although both methods have shown a beneficial impact.