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Pigmentation disorders are disturbances of human skin color. [1] There may be a loss or reduction, which may be related to loss of melanocytes or the inability of melanocytes to produce melanin or transport melanosomes correctly. [1] Most pigmentation disorders involve the underproduction or overproduction of melanin. [2] [3]
This is an accepted version of this page This is the latest accepted revision, reviewed on 14 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
A variety of diseases and abnormal conditions that involve pigmentation are in humans and animals, either from absence of or loss of pigmentation or pigment cells, or from the excess production of pigment. Albinism is an inherited disorder characterized by total or partial loss of melanin. Humans and animals that suffer from albinism are called ...
If you want to go the retinoid route for blocking pigmentation and fighting discoloration, Dr. Miller recommends a cult classic that’s typically associated with treating acne: Differin 0.1% Gel ...
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.
Pigmentation including tanning is under hormonal control, including the MSH and ACTH peptides that are produced from the precursor proopiomelanocortin. Vitiligo is a skin disease where people lack melanin in certain areas in the skin. People with oculocutaneous albinism typically have a very low level of melanin production.
"Although the rash is not dangerous, it can be quite distressing to people who have noted it very challenging to decrease the redness and decrease the increased pigmentation on their skin," says ...
Pigmentation increases the heat load in hot climates, and dark-skinned people absorb 30% more heat from sunlight than do very light-skinned people, although this factor may be offset by more profuse sweating. In cold climates dark skin entails more heat loss by radiation. Pigmentation also hinders synthesis of vitamin D. Since pigmentation ...