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Persons suffering from metallosis can experience any of the following symptoms: Extreme pain (even when not moving); Swelling and inflammation; [17] Loosening of the implant; Joint dislocation; Bone deterioration; Aseptic fibrosis, local necrosis; [18] [17] Hip replacement failure; Metal toxicity from grinding metal components; and
There are reports of cobalt toxicity with hip replacement, particularly metal-on-metal hip replacements, which are no longer in use. [49] [50] Use of metal-on-metal hip replacements from the 1970s was discontinued in the 1980s and 1990s, particularly after the discovery of aseptic lymphocyte-dominant vasculitis-associated lesions (ALVAL).
Many metals, particularly heavy metals are toxic, but some are essential, and some, such as bismuth, have a low toxicity. Metals in an oxidation state abnormal to the body may also become toxic: chromium(III) is an essential trace element, but chromium(VI) is a carcinogen. Only soluble metal-containing compounds are toxic. Soluble metals are ...
Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of vitamin B 12 . A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia .
Doctors discovered Jackson to have lost all of the cartilage supporting his hip while he was undergoing tests following a hip injury he had on the field during a 1991 NFL Playoff game. [29] Avascular necrosis of the hip was also identified in a routine medical check-up on quarterback Brett Favre following his trade to the Green Bay Packers in ...
Serious toxicity problems have resulted from long-term exposure to cadmium plating baths. Workers can be exposed to cadmium in air from the smelting and refining of metals, or from the air in plants that make cadmium products such as batteries, coatings, or plastics. Workers can also be exposed when soldering or welding metal that contains cadmium.
Medical Device Alert: DePuy ASR TM acetabular cups used in hip resurfacing arthroplasty and total hip replacement, Medicines and Healthcare products Regulatory Agency, MDA/2010/044, 25 May 2010; Medical Device Alert: All metal-on-metal (MoM) hip replacements, Medicines and Healthcare products Regulatory Agency, MDA/2012/008, 28 February 2012
People who ingest many coins will have elevated zinc levels, leading to zinc-toxicity-induced copper deficiency and the associated neurological symptoms. This was the case for a 57-year-old woman diagnosed with schizophrenia. The woman consumed over 600 coins and started to show neurological symptoms such as unsteady gait and mild ataxia. [17]