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The liver stiffness is significantly higher in the cirrhotic liver. Transient elastography was initially called time-resolved pulse elastography [15] when it was introduced in the late 1990s. The technique relies on a transient mechanical vibration which is used to induce a shear wave into the tissue.
MR elastography for detection of liver fibrosis in two patients. The left column shows the anatomy, with the liver outlined. The middle row shows images of propagating shear waves in the liver, captured with the MRE technique. The right column shows elastograms computed from the wave images, with tissue stiffness depicted with on color scale.
Tomoelastography of the abdomen; upper a healthy state, lower with malignancy.. Tomoelastography (from ancient Greek τόμος tomos, “slice” and elastography – imaging of viscoelastic properties) is a medical imaging technique that provides quantitative maps of the mechanical properties of biological soft tissues with high spatial resolution (called elastograms).
The current imaging protocol for a hepatogram is magnetic resonance elastography for fibrosis and inflammation assessment, and proton density fat fraction for steatosis measurement. A hepatogram is seen as a more accurate and noninvasive alternative to liver biopsy, and has emerged as "the reference standard for non-invasive diagnosis of liver ...
Liver cirrhosis makes it hard for blood to flow in the portal venous system. [39] This resistance creates a backup of blood and increases pressure. [39] This results in portal hypertension. Effects of portal hypertension include: Ascites is a build-up of fluid in the peritoneal cavity in the abdomen [40] An enlarged spleen in 35–50% of cases [6]
The first OCT elastography of arteries was done by the Brezinski group in 2004 [9] But the term optical coherence elastography was first coined in a 2004 paper with Brett Bouma. [ 10 ] Requiring no injections, OCE is a non-invasive imaging method can gives more details than ultrasound or MRI .
Medical ultrasound includes diagnostic techniques (mainly imaging techniques) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints, blood vessels, and internal organs, to measure some characteristics (e.g., distances and velocities) or to generate an informative audible sound.
The parallel-plate flow chamber, in its original design, is capable of producing well-defined wall shear-stress in the physiological range of 0.01-30 dyn/cm 2.Shear stress is generated by flowing fluid (e.g., anticoagulated whole blood or isolated cell suspensions) through the chamber over the immobilized substrate under controlled kinematic conditions using a syringe pump.