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Talizumab (TNX-901) is a humanized monoclonal antibody that was under development by Tanox in Houston, Texas as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils.
Among the humanized antibody drugs Tanox developed by itself or with corporate partners: . Omalizumab, trade name Xolair; TNX-901, also referred to as talizumab.Two leading allergy researchers, Donald Leung and Hugh Sampson, led a team of clinical investigators and performed a double-blinded, randomized, dose-ranging, multi-center trial of TNX-901 in 84 patients with a history of immediate ...
John P. McGovern (June 2, 1921 - May 31, 2007) was an American allergist, investor and philanthropist.He established the McGovern Allergy Clinic in Houston, Texas, created the Texas Allergy Research Foundation [1] and the John P. McGovern Foundation, and co-founded the American Osler Society.
Asthma is one of the most common lung diseases in the world, affecting some 262 million people worldwide and causing more than 450,000 deaths annually, per the World Health Organization.While ...
Spring allergy season has arrived with sneezes and sniffles. But allergies are more severe in some areas of the country than others. Many of the most challenging cities to live in for people with ...
Asthma and Allergy Foundation of America, Allergy Facts and Figures, Accessed 09/07/22. Clifford Bassett, M.D., allergist at NYU Langone Health based in New York City.
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