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Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.Some lipase inhibitors have been identified in Panax ginseng. [5] [6] Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase.
30924 Ensembl ENSG00000132855 ENSMUSG00000028553 UniProt Q9Y5C1 Q9R182 RefSeq (mRNA) NM_014495 NM_013913 RefSeq (protein) NP_055310 NP_038941 Location (UCSC) Chr 1: 62.6 – 62.61 Mb Chr 4: 98.92 – 98.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Angiopoietin-like 3, also known as ANGPTL3, is a protein that in humans is encoded by the ANGPTL3 gene. Function The protein encoded ...
Lipase inhibitors belong to a drug class that is used as an antiobesity agent. Their mode of action is to inhibit gastric and pancreatic lipases, enzymes that play an important role in the digestion of dietary fat. [2] Lipase inhibitors are classified in the ATC-classification system as A08AB (peripherally acting antiobesity products). [3]
Pages in category "Lipase inhibitors" The following 5 pages are in this category, out of 5 total. This list may not reflect recent changes. ...
Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase.
Ibrolipim (NO-1886) is a cholesterol lowering drug from the statin family, which acts as a lipoprotein lipase activator. The discovery of the "statin" mevalonic acid synthesis inhibitors focused new attention on control of blood lipid levels as a measure to stave off heart disease.
In a 2012 study, for example, 385 participants with obesity followed a lifestyle program and took either a placebo or topiramate for 24 weeks. Those on topiramate started on a daily dose of 16mg ...
Picture depicts role of ANGPTL4 as endogenous inhibitor of lipoprotein lipase and its regulation by fatty acids via Peroxisome Proliferator Activated Receptors. This gene is induced under hypoxic (low oxygen) condition in various cell types and is the target of peroxisome proliferator-activated receptors. The encoded protein is a serum hormone ...