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Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions. [27]
James Parkinson. Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms usually emerge slowly, and, as the disease progresses, non-motor symptoms become more common. Usual symptoms include tremors, slowness ...
The demonstration of deficits in producing and understanding emotional information in modalities other than speech prosody (e.g. facial and gestural) in individuals with Parkinson's disease, as well as in individuals with other disorders affecting basal ganglia circuitry, are providing increasing evidence for an additional non-motorically based ...
Hypomimia (masked faces, masking of faces, mask-like facial expression), a medical sign, is a reduced degree of facial expression. It can be caused by motor impairment (for example, weakness or paralysis of the facial muscles), as in Parkinson's disease, or by other causes, such as psychological or psychiatric factors (for example, if a patient ...
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1][2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3] These are the four motor symptoms found in Parkinson's ...
The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. [1] The UPDRS is made up of these sections: [2] Part I: evaluation of mentation, behavior, and mood