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A 2-D model of cortical sensory homunculus. A cortical homunculus (from Latin homunculus 'little man, miniature human' [1] [2]) is a distorted representation of the human body, based on a neurological "map" of the areas and portions of the human brain dedicated to processing motor functions, and/ or sensory functions, for different parts of the body.
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. Afferent in this case means bringing information from the body's periphery toward the brain.
A nerve that supplies information to the brain from an area of the body, or controls an action of the body is said to innervate that section of the body or organ. Other terms relate to whether the nerve affects the same side ("ipsilateral") or opposite side ("contralateral") of the body, to the part of the brain that supplies it.
With the advent of the electron microscope in the early 1950s, nerve endings were found to contain a large number of electron-lucent (transparent to electrons) vesicles. [27] [28] The term synaptic vesicle was first introduced by De Robertis and Bennett in 1954. [29]
The meninges of the brain and medulla spinalis; The cerebrospinal fluid; The cranial nerves. The olfactory nerves; The optic nerve; The oculomotor nerve; The trochlear nerve; The trigeminal nerve; The abducens nerve; The facial nerve; The vestibulocochlear nerve; The glossopharyngeal nerve; The vagus nerve; The accessory nerve; The hypoglossal ...
Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs.Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck, including the special senses of vision, taste, smell, and hearing.
A nociceptor (from Latin nocere 'to harm or hurt'; lit. ' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain.
The vanilloid receptor (VR-1, TRPV1) is a receptor that is found on the free nerve endings of both C and Aδ fibers that responds to elevated levels of heat (>43 °C) and the chemical capsaicin. [10] Capsaicin activates C fibers by opening a ligand-gated ion channel and causing an action potential to occur. [10]