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The drug is predominantly active against HSV and, to a lesser extent, VZV. It is only of limited efficacy against EBV and CMV. However, valaciclovir has been shown to lower or eliminate the presence of the Epstein–Barr virus in subjects afflicted with acute mononucleosis, leading to a significant decrease in the severity of symptoms.
The recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir taken twice a day. In addition to preventing outbreaks, these medications greatly reduce the chance of infecting someone while the patient is not having an outbreak. [citation needed]
In 2009, acyclovir in combination with hydrocortisone cream, marketed as Xerese, was approved in the United States for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (six years of age and older).
Oral herpes involves the face or mouth. It may result in small blisters in groups, often called cold sores or fever blisters, or may just cause a sore throat. [2] [6] Genital herpes involves the genitalia. It may have minimal symptoms or form blisters that break open and result in small ulcers. [1] These typically heal over two to four weeks. [1]
“Most colds last from seven to 10 days and will resolve on their own but it's normal to feel terrible with a cold. The mainstay of cold treatment is to manage the symptoms,” Dr. Agyemang says.
Cold sore; Other names: fever blister, [1] herpes labialis, [1] oral herpes, [2] orolabial herpes [3] A cold sore on the lower lip. Note the blisters in a group marked by an arrow. Specialty: Infectious disease: Symptoms: Burning pain followed by small blisters or sores [1] Complications: Herpes encephalitis, herpetic whitlow [4] Usual onset ...